Blot attachment in ASC

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What is the function of the ASC gene?

Results suggest that apoptosis-associated speck-like protein (ASC) can function as an adaptor molecule for Bax and regulate a p53-Bax mitochondrial pathway of apoptosis. Methylation-mediated silencing of TMS1/ASC confers a survival advantage to ovarian tumor cells.

What is signature ASC?

An ASC signature file is contained in an ASCII-Armored file and uses the . asc file extension. ASCII-armor puts binary data into ASCII and adds headers that provide information about the data inside. An ASCII-Armored PGP key file uses the . asc extension as well.

What is apoptosis associated speck like protein containing a caspase recruitment domain ASC?

The apoptosis-associated Speck-like protein containing a caspase-1 recruitment domain (ASC), present in inflammasomes, regulates inflammation events and is involved in osteogenic phenotype.

What is apoptosis associated speck like protein ASC?

PYCARD, often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD), is a protein that in humans is encoded by the PYCARD gene. It is localized mainly in the nucleus of monocytes and macrophages.

What is the ASC protein?

Apoptosis-associated speck-like protein containing a caspase recruitment domain (CARD) (ASC) is a 22 kDa protein that functions as the central adaptor for inflammasome assembly.

What are ASC specks?

ASC specks are micrometer-sized structures formed by the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD). ASC specks are characteristic of inflammasome activation. The inflammasome adapter ASC is localized mainly in the nucleus of macrophages and monocytes.

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