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[Applause] hi all welcome to our channel myself dr naga prashanth in this video we are going to see about molecular talking and important components of molecular docking before starting that let us see the history of molecular docking the year of 1981 a cover article which was entitled next industrial revolution designing drugs by computer at mark has been published by fortune magazine this event may be regarded as the beginning of potential interests among scientists towards cad this is the very beginning of cad and its utilization among the scientists for the discovery of new leads later on in the past decade cad has been re-emerged as a very effective way to develop new potential drugs most of the pharmaceutical companies have started using or utilizing cad the major two things which are making companies to use cad is reduction of the cost and reduction of workload the screening of a number of molecules can be easily executed in order to lead the compound discovery many comp