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we did this study to see if nitrates help patients who have a certain type of heart failure due to a stiff heart called heart failure with preserved ejection fraction to see if nitrates could help these patients be more active about 6 million people in the United States now have heart failure half of those have this special type of heart failure where the heart is stiff and causes problems with the ability to be active in to tolerate activity so its a pretty big problem what we found is that during the time the patients were taking nitrates they were actually less active than when they were taking the placebo medicine further we found that when they were taking the nitrate they didnt have better performance on an exercise test and they didnt have better symptoms as assessed by a symptom score that assesses heart failure symptoms physicians frequently treat these types of heart failure patients with nitrates to try and help them feel better I think what we found is that probably due